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  1. Spectrometry for Sample Analysis: Technique Overview

    Spectrometry for Sample Analysis: Technique Overview

    Several options exist for determining the composition, concentration, and purity of a laboratory sample. Among the most commonly used techniques are Ultraviolet/Visible (UV/Vis), Infrared (IR), and Atomic Absorption Spectrometry. Each technique is capable of providing some or all of these pieces of …

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  2. Movers & Shakers: what mixer for my application?

    Movers & Shakers: what mixer for my application?

    Instrument options abound for preparing, incubating, washing, or chemical fixation of samples using kinetic motion. Lab mixers that include orbital shakers, vortexes, rockers, rollers and rotators are all offered in a variety of configurations (capacity, speed, duration, slope and more). These …

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  3. Microarray Platforms: Beads, Slides or Chips?

    Microarray Platforms: Beads, Slides or Chips?

    Since its advent in 1995, miniaturized microarray analysis has become a mainstay analytical technique of genomic, proteomic, pharmaceutical and clinical laboratories worldwide. The initial microarray chips, developed by Pat Brown at Stanford University, utilized oligonucleic acid probes deposited …

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  4. Cell Disruption: Sonication vs. Homogenization

    Cell Disruption: Sonication vs. Homogenization

    The preparation of samples for protein and nucleic acid analysis requires two essential steps: disruption of the tissue to release individual cells and lysis of those cells to release their cellular contents. Mechanical homogenization and sonication (sometimes referred to as ultrasonic …

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  5. Selecting a Cryoprotectant for Eukaryotic & Bacterial Cell Storage

    Selecting a Cryoprotectant for Eukaryotic & Bacterial Cell Storage

    The cryoprotectant your lab selects for long-term storage of both eukaryotic and bacterial cell storage can have profound implications for future experimental results. Cryoprotectants, literally “to protect cells and tissue from damage due to freezing,” can be man-made, or generated in nature. For …

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  6. Consider CO2 When Selecting a Lab Incubator

    Consider CO2 When Selecting a Lab Incubator

    Incubators have traditionally been a mainstay for most biological and life science laboratories, to grow or sustain biological cultures, reproduce germ colonies or breed/grow insects. The most basic incubators allow researchers to recreate strict temperature conditions for optimal growth, …

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  7. Applications for Laboratory Ovens Across the Sciences

    Applications for Laboratory Ovens Across the Sciences

    Laboratory ovens are used in a wide range of applications in industries such as biotech, pharmaceuticals and materials manufacturing. These industries often require the process of baking, curing, annealing and drying materials of varying chemical and physical compositions. Many of these process …

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  8. Absorption Spectroscopy in Pharmaceutical Analysis

    Absorption Spectroscopy in Pharmaceutical Analysis

    USP Compliance of Pharmaceutical Labs Absorption spectroscopy is an important analytical chemistry technique used in pharmaceutical analysis. The United States Pharmacopeia (USP) defines absorption spectroscopy as “the measurement of an interaction between electromagnetic radiation and the …

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  9. Preventing Contamination in PCR Reactions

    Preventing Contamination in PCR Reactions

    Polymerase Chain Reaction (PCR), the amplification of DNA, is an established process used in molecular biology. PCR technology has made strides in medical and infectious disease diagnoses, forensics and research applications. Decisions about treatment options and clinical efficacy are often based …

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  10. Advantages of Lyophilization for Long-Term Sample Storage

    Advantages of Lyophilization for Long-Term Sample Storage

    Lyophilization, also known as freeze-drying or cryo-desiccation, is the process by which water is removed from a sample without the need to apply heat. Many labs prefer the process of lyophilization over direct heat when it comes to long-term sample storage since freeze-drying prevents sample …

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