Swinging Bucket vs. Fixed Angle Rotors
A process that normally takes hours or days under the force of normal gravity (1 g) can be shortened to minutes when a force of 10,000 g is applied with a relatively inexpensive and easy-to-use piece of equipment. The faster the centrifuge turns (i.e., the higher the RPM), the faster the faster the sedimentation. Relative centrifugal force (RCF) is another way of expressing the gravitational force (g-force), or the turning of the rotor, which allows researchers to easily separate tissues, cells, organelles, and macromolecules for further investigation.