All Laboratory-Equipment Blogs

  1. Lyophilizer Features Comparison - Freeze Dryers for Microbiology and Pharmaceuticals

    Lyophilization, or freeze drying, is a common technique used in the pharmaceutical and food industries to vacuum freeze samples for long-term, ambient storage.

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  2. Pipette Features Comparison

    Pipettes are the primary means for transferring liquids, often in milliliter and microliter volumes, into test tubes, microplates, and conical vials for analysis, storage or mixing. Pipettes aspirate a user-selected volume of liquid – samples, reagents, media – from one vessel, then dispense the set volume of liquid into another vessel according to standard operating procedures. Pipettes, or pipettors, are available in a broad range of designs (single-channel or multi-channel), volume ranges, and control systems (mechanical and electronic) for different applications and experience levels.

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  3. Compare Liquid Nitrogen Storage Tanks, Freezers, Vessels, and Dewars

    Liquid nitrogen vessels are designed to support long-term storage of samples at cryogenic temperatures (-196°C to -210°C). The process of cryo-preservation is widely used in clinical diagnostics, immunotherapy development, food and beverage, and semiconductor storage. Samples prepared with cryo-protectants, such as DMSO, can remain viable for up to a decade when stored in liquid nitrogen.

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  4. Incubator Features Comparison

    Lab incubators and environmental test chambers are designed to maintain environmental conditions ideal for growing and storing bacterial and mammalian cell cultures.

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  5. Gel Electrophoresis Features Comparison

    Gel electrophoresis systems utilize a porous, electrically-charged gel matrix to separate distinct nucleic acid and protein sequences based on molecular weight (or fragment size). The gel box is designed to include a cathode, or negatively-charged electrode, at one end of the medium and an anode, or positive-charged electrode, at the opposite end.

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  6. Gel Electrophoresis Stain: What to Use?

    Gel Electrophoresis Stain: What to Use?

    Electrophoresis is a common lab procedure for identifying and separating macromolecules. It was first observed in the early 1800s by a university scientist in Moscow. Like many discoveries, it was accidental, but has proven itself useful for many research scenarios. By applying electricity, technicians use the particles’ negative or positive charges to make them migrate through porous matrix, such as an agarose gel. When positively charged molecules are present in a sample, they will creep towards the negative current (cathode), while negatively charged molecules will migrate to the positive current (anode).

    Besides a source of electricity and gel, this kinetic test requires buffer to help prevent temperature and pH extremes. The type of gel used depends on the sample and application. Gels are “solid,” but porous. Within the gel, larger molecules will travel more slowly and smaller molecules will move quickly. Therefore, molecular size is another w

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  7. BioSafety Levels 1 & 2: What’s the Difference?

    BioSafety Levels 1 & 2: What’s the Difference?

    The United States Center for Disease Control (CDC) has developed guidelines to classify laboratory applications conducted with potentially hazardous biological microorganisms. These levels range from Biosafety Level 1 (the least hazardous) to Biosafety Level 4 (the most hazardous).

    In addition to specifying guidelines for the type of work that is classified under each Biosafety Level (BSL), the CDC also has guidelines for the types of precautions and protections needed to mitigate injury resulting from exposure to pathogens. These Biosafety Level protocols have been used by manufacturing companies as references for engineering controls such as biosafety cabinets and glove box enclosures. Creating a secure working environment is a critical goal of the CDC and individual employers.

    Continue reading to learn the specific differences between the CDC’s first two Biosafety Levels.

    Biosafety Le
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  8. Centrifuge Rotor Types: Swinging Bucket vs. Fixed Angle

    Centrifuge Rotor Types: Swinging Bucket vs. Fixed Angle

    Centrifugation is one of the most widely used laboratory techniques for the separation of materials in the fields of biochemistry, molecular biology, medicine, food sciences and industry. It’s all about gravity and mass: particles in a heterogeneous solution will, given enough time, separate based on their size and density. Smaller, less-dense particles may also migrate down, but not always; some particles will never settle, but remain suspended in solution. Centrifuges force this process along much more quickly and efficiently. Its uses have proven to be so powerful and wide-spread across the sciences that centrifuges have been a common piece of laboratory equipment since the late 19th century.

    Centrifuge tube showing separation
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  9. What Type of Laboratory Water Do I Need?

    What Type of Laboratory Water Do I Need?

    Water’s ability to dissolve compounds, along with its polarity, bonding, melting, boiling and freezing points, heat absorption, and vaporization characteristics arguably make it the most versatile substance we know. It’s also ubiquitous and plentiful: the earth can’t live without it, most plants and animals can’t exist without it, and scientists can’t operate labs without it.

    Water is the most common reagent used in the laboratory, and while water quality can often be overlooked, the grade of water being used in an application is critical. Minute traces of salts or biological contaminants can result in unfortunate consequences when culturing cells or performing analytical measurements of biological macromolecules.

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  10. Horizontal vs. Vertical Gel Electrophoresis Systems

    Horizontal vs. Vertical Gel Electrophoresis Systems

    Gel electrophoresis allows for the separation of nucleic acids (DNA or RNA) and proteins based on their size. Electrophoresis is used by labs studying vaccines, medications, forensics, DNA profiling or other life science applications. The technique is also used in industry such as mining or food sciences.

    Gel electrophoresis utilizes a porous gel matrix through which proteins or nucleic acids migrate. Both nucleic acids and proteins possess a net-negative electrical charge, a property that is leveraged to facilitate the migration of the desired molecule through the medium.

    The gel box features a cathode at one end and an anode at the other. The box is filled with an ionic buffer, which creates an electric field when a charge is applied. Since the proteins and nucleic acids have a uniformly negative charge, the molecules will migrate towards the positive electrode. The speed of this migration is dependent on how easily the molecules move through the pores of

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