What are Anaerobic and Hypoxia Glove Boxes?

Researchers have been culturing bacterial and eukaryotic cells for decades in an effort to elucidate their biological functions and to develop and evaluate treatments for disease. While culturing cells under atmospheric conditions may yield informative results, often these studies require an environment that more closely mimics the actual physiological climate.

In vivo, animal cells are exposed to oxygen concentrations that range from 1% to 12%. At normal atmospheric conditions, oxygen is present at a concentration of around 21%. Many anaerobic microorganisms cannot carry out proper metabolic processes in the presence of oxygen. In fact, atmospheric concentrations of oxygen are often toxic to these cells.

To confront these challenges, researchers have developed specialized chambers to encourage the growth of both bacterial and eukaryotic cells in an effort to investigate their physiological functions and develop treatments for diseases. Read more ab

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